The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 18, 2022
Filed:
May. 08, 2020
Applicant:
The Feinstein Institutes for Medical Research, Manhasset, NY (US);
Inventors:
Yousef Al-Abed, Manhasset, NY (US);
Huan Yang, Manhasset, NY (US);
Assignee:
THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH, Manhasset, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 38/07 (2006.01); A61K 38/00 (2006.01); A61K 9/08 (2006.01); A61P 25/02 (2006.01); C07K 5/10 (2006.01); A61K 9/00 (2006.01); C07K 1/113 (2006.01); A61K 47/65 (2017.01); C07K 14/47 (2006.01); A61K 31/197 (2006.01); C07K 5/107 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A61K 9/007 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0043 (2013.01); A61K 9/0053 (2013.01); A61K 31/197 (2013.01); A61K 38/07 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/65 (2017.08); A61P 25/02 (2018.01); C07K 1/113 (2013.01); C07K 5/1016 (2013.01); C07K 14/4703 (2013.01); A61K 9/08 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention is related to HMGB1 antagonists and, in particular, HMGB1 tetramer peptidomimetics which have been stabilized with at least one azatide linkage, such as K883. The present invention is also related to pharmaceutical compositions comprising HMGB1 antagonists such as K883.