The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Feb. 28, 2020
Applicants:

Rowan University, Glassboro, NJ (US);

The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);

Inventors:

Thomas M. Keck, Philadelphia, PA (US);

Christopher A. Lowry, Boulder, CO (US);

Assignees:

Rowan University, Glassboro, NJ (US);

The Regents of the University of Colorado, Denver, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61P 25/30 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); A61P 25/30 (2018.01);
Abstract

The present invention provides compositions and methods for treating, ameliorating, and/or preventing cocaine addiction in a subject. Immunization byalters serotonin signaling in the brain, reducing stress- and anxiety-like responding in animal models of post-traumatic stress disorder and other anxiety disorders. In certain embodiments, the immunoregulatory, anti-stress, and anxiolytic effects ofimmunization reduces addiction- and relapse-like responding in models of cocaine addiction and alter the development of cocaine-induced neuroinflammation.


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