The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Nov. 10, 2017
Applicants:

Universidade DE Santiago DE Compostela, a Coruña, ES;

Universidad Autónoma DE Madrid, Madrid, ES;

Inventors:

Jessica Rodríguez Villar, Santiago de Compostela, ES;

José Luis Mascareñas Cid, Santiago de Compostela, ES;

José Rodríguez Couceiro, Santiago de Compostela, ES;

Jesús Mosquera Mosquera, Santiago de Compostela, ES;

Marcos Eugenio Vázquez Sentís, Santiago de Compostela, ES;

Bruno Sainz Anding, Madrid, ES;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/555 (2006.01);
U.S. Cl.
CPC ...
A61K 31/555 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to the use of ruthenium(II) complexes for preparing a medicinal product for treating cancer, particularly cancer comprising cancer stem cells. Said ruthenium complexes are capable of selectively metallating guanine quadruplexes, thus resulting in increased expression of the c-MYC oncogene. This increase in the proportion of c-MYC may promote the differentiation of cancer stem cells.


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