The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 2022

Filed:

Aug. 26, 2021
Applicant:

Small Pharma Ltd, London, GB;

Inventors:

Peter Rands, London, GB;

Tiffanie Benway, London, GB;

Zelah Joel, London, GB;

Marie Layzell, London, GB;

Ellen James, London, GB;

Assignee:

Small Pharma Ltd, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/16 (2006.01); A61K 9/48 (2006.01); A61K 31/4045 (2006.01); A61K 9/00 (2006.01); A61K 9/50 (2006.01); A61K 9/20 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/485 (2013.01); A61K 9/0053 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01); A61K 9/5057 (2013.01); A61K 31/4045 (2013.01); C07B 59/002 (2013.01); C07D 209/16 (2013.01); C07B 2200/05 (2013.01);
Abstract

Compounds, compositions, methods, and uses are described for therapeutic deuterated N,N-dimethyltryptamine compounds (e.g., a single compound or a plurality of deuterated N,N-dimethyltryptamine compounds) such as N,N-dimethyltryptamine compounds, α-protio, α-deutero-N,N-dimethyltryptamine compounds, α,α-dideutero-N,N-dimethyltryptamine compounds, and pharmaceutically acceptable salts of these compounds. The deuterated N,N-dimethyltryptamine compound may have an increased half-life compared with the half-life of undeuterated N,N-dimethyltryptamine. For example, a deuterated N,N-dimethyltryptamine compound may be used in therapy and have a Formula (I):


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