The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Jul. 29, 2021
Shandong Institute for Food and Drug Control, Shandong, CN;
Shandong University, Shandong, CN;
Avanc Pharmaceutical Co., Ltd, Liaoning, CN;
Feng Shi, Shandong, CN;
Ruiqing Xian, Shandong, CN;
Liping Gong, Shandong, CN;
Weijian Wang, Shandong, CN;
Lianli Chi, Shandong, CN;
Congcong Wang, Shandong, CN;
Baojian Hang, Shandong, CN;
Xunjie Zhang, Shandong, CN;
Li Nie, Liaoning, CN;
Fengshan Wang, Shandong, CN;
Shandong Institute for Food and Drug Control, Shandong, CN;
Shandong University, Shandong, CN;
Avanc Pharmaceutical Co., Ltd, Liaoning, CN;
Abstract
The present invention relates to the field of chemical analysis detection and application, in particular to a marker peptide of snake venom thrombin-like enzymes (SVTLEs) fromand an application thereof. The amino acid sequence of the marker peptide of snake venom thrombin-like enzymes (SVTLEs) fromis TLCAGVMEGGIDTCNR. Characterizing the source of species and a content of the SVTLEs in a to-be-detected sample by using the marker peptide includes the following steps of: pretreating the to-be-detected sample by trypsin through enzymolysis, and taking a supernatant of an enzymolysis liquid as a test solution; and injecting the test solution and a reference solution into a liquid chromatography-mass spectrometer, and selecting a qualitative ion pair and a quantitative ion pair for detecting the source of species and a content of the SVTLEs in the to-be-detected sample.