The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2022

Filed:

Dec. 31, 2018
Applicants:

Korea Advanced Institute of Science and Technology, Daejeon, KR;

Bionano Health Guard Research Center, Daejeon, KR;

Inventors:

Hyun Gyu Park, Daejeon, KR;

Hyo Yong Kim, Daejeon, KR;

Yong Ju, Daejeon, KR;

Jun Ki Ahn, Daejeon, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/683 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/683 (2013.01); C12Y 207/07049 (2013.01);
Abstract

The present invention relates to a detection method for detecting a target RNA contained in a sample with high sensitivity by using nicking/extension chain reaction system-based isothermal nucleic acid amplification (NESBA) that uses activity of a cleavage enzyme and a DNA polymerase. The NESBA of the present invention is a new concept isothermal target RNA detection method that realizes higher amplification efficiency than the existing NASBA technology and is deemed to be utilizable as a new concept diagnosis technology that can replace conventional target RNA detection technologies.


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