The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Aug. 15, 2019
396419 B.c. Ltd., Victoria, CA;
Albert Einstein College of Medicine, Bronx, NY (US);
Carl Erickson, Corte Madera, CA (US);
Christopher P. Rusconi, Durham, NC (US);
Kevin G. McLure, Oakland, CA (US);
Matthew Levy, Cary, NC (US);
Arijit Bhowmick, Durham, NC (US);
396419 B.C. Ltd., Victoria, CA;
Albert Einstein College of Medicine, Bronx, NY (US);
Abstract
The application discloses methods and compositions for the inhibition of the alternative complement pathway. The methods and compositions involve the use of aptamers for inhibiting complement Factor D. The application further provides anti-Factor D aptamers for the treatment of dry age-related macular degeneration, geographic atrophy, wet age-related macular degeneration or Stargardt disease. In some cases, stem-loop aptamers are provided for the inhibition of Factor D.