The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Feb. 20, 2020
Bristol-myers Squibb Company, Princeton, NJ (US);
Marek Honczarenko, Princeton, NJ (US);
Vaishali Shah, Pennington, NJ (US);
Lixin Lang, Princeton, NJ (US);
Urvi Aras, Kendall Park, NJ (US);
Diane Shevell, Westfield, NJ (US);
Christine Kratt, Fort Collins, CO (US);
Karen Price, Sauquoit, NY (US);
Suzanne Suchard, Portland, OR (US);
BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);
Abstract
Methods of treating autoimmune diseases, such as primary immune thrombocytopenia (ITP), solid organ transplant rejection, graft-related disease, pemphigus vulgaris, systemic sclerosis, and myasthenia gravis using antibody polypeptides that specifically bind human CD40L are provided. The antibody polypeptides do not activate platelets. The methods may comprise at least one administration cycle comprising one dose of the antibody polypeptide. The dose may be administered intravenously at a dose from about 75 mg to about 1500 mg. The method normalizes platelet counts in the human patient.