The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Sep. 11, 2014
The Administrators of the Tulane Educational Fund, New Orleans, LA (US);
Duquesne University of the Holy Ghost, Pittsburgh, PA (US);
Suravi Chakrabarty, Pittsburgh, PA (US);
Patrick T. Flaherty, Pittsburgh, PA (US);
Darlene Monlish, Clayton, MO (US);
Jane E. Cavanaugh, Pittsburgh, PA (US);
Matthew E. Burow, Slidell, LA (US);
Steven Elliott, New Orleans, LA (US);
Van T. Hoang, New Orleans, LA (US);
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, New Orleans, LA (US);
DUQUESNE UNIVERSITY OF THE HOLY GHOST, Pittsburgh, PA (US);
Abstract
Disclosed are anthranilic amide derivatives having the formula. Compositions are disclosed that include the anthranilic amide derivatives and the use of the anthranilic amide derivatives for the manufacture of a medicament. Further disclosed are methods of inhibiting or treating cancer, inhibiting or reversing an epithelial to mesenchymal cellular transition, and/or inhibiting MEK1/2 and/or MEK 5 enzymatic activity in a subject by administering to the subject an effective amount of a disclosed anthranilic amide derivative.