The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Aug. 01, 2020
Applicant:
Aurigene Discovery Technologies Limited, Bangalore, IN;
Inventors:
Pottayil Govindan N. Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Seetharamaiah Setty Sudarshan Naremaddepalli, Bangalore, IN;
Assignee:
Aurigene Discovery Technologies Limited, Bangalore, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); C07D 271/06 (2006.01); A61P 35/00 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 271/10 (2006.01); C07K 5/087 (2006.01); A61K 38/05 (2006.01); A61K 45/06 (2006.01); C07K 5/065 (2006.01);
U.S. Cl.
CPC ...
C07D 271/06 (2013.01); A61K 31/4245 (2013.01); A61K 38/05 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 271/10 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07K 5/06078 (2013.01); C07K 5/0812 (2013.01);
Abstract
The present invention relates to 1,2,4-oxadiazole and thiadiazole compounds of formula (I) and their use to inhibit the programmed cell death 1 (PD1) signaling pathway and/or for treatment of disorders by inhibiting an immunosuppressive signal induced by PD-1, PD-L1 or PD-L2.