The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Nov. 25, 2019
Applicant:
Orthopaedic Research Uk, London, GB;
Inventors:
Assignee:
ORTHOPAEDIC RESEARCH UK, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61K 49/14 (2006.01); A61K 49/18 (2006.01); A61K 49/04 (2006.01); B82Y 5/00 (2011.01); A61K 47/69 (2017.01); A61B 6/03 (2006.01); A61K 38/17 (2006.01); G01R 33/56 (2006.01); A61P 19/08 (2006.01);
U.S. Cl.
CPC ...
A61K 49/14 (2013.01); A61B 6/032 (2013.01); A61K 38/1793 (2013.01); A61K 47/6929 (2017.08); A61K 49/0428 (2013.01); A61K 49/1875 (2013.01); B82Y 5/00 (2013.01); G01R 33/5601 (2013.01); A61K 49/1866 (2013.01); A61P 19/08 (2018.01);
Abstract
A bone biospecific agent comprises a contrast material core, which is visible using Magnetic Resonance Imaging (MRI) or Computed Tomography (CT). The contrast material core is surrounded by a polymeric shell, which is functionalised with a bone-targeting peptide. In use, the peptide targets the biospecific agent to bone. The bone biospecific agent can be used in diagnostic imaging techniques, such as MRI and CT, and in imaging bone remodelling activities, detecting and treating pathological bone conditions and/or bone repair processes. The invention extends to the diagnosis and/or treatment of bone disease and bone pathologies using the biospecific agents.