The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Nov. 19, 2019
Applicant:
Boston Medical Center Corporation, Boston, MA (US);
Inventor:
Richard N. Goldstein, Cambridge, MA (US);
Assignee:
Boston Medical Center Corporation, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/09 (2006.01); A61P 31/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/092 (2013.01); A61P 31/04 (2018.01); A61K 2039/55505 (2013.01); A61K 2039/575 (2013.01);
Abstract
Cold spot genes ofare disclosed that encode surface proteins that are universally conserved among known strains and have exceptionally low incidence of allelic variation. Cold spot polypeptides encoded by the genes that are antigenic on thecells on which they are expressed are candidates for immunogenic compositions capable of eliciting antibodies able to react with all or nearly all strains of, thus providing an improvement over currently availablevaccines that protect inoculated individuals against a maximum of about 23 of the 94 or so known serotypes of