The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2022

Filed:

Oct. 11, 2017
Applicant:

Unicyte Ev Ag, Oberdorf, CH;

Inventors:

Maria Felice Brizzi, Turin, IT;

Giovanni Camussi, Turin, IT;

Andrea Ranghino, Turin, IT;

Assignee:

USICYTE EV AG, Oberdorf, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/078 (2010.01); G01N 33/50 (2006.01); A61P 9/10 (2006.01); A61K 35/12 (2015.01); A61K 35/14 (2015.01); A61P 17/02 (2006.01); A61K 9/127 (2006.01); A61K 35/16 (2015.01);
U.S. Cl.
CPC ...
A61K 35/14 (2013.01); A61K 9/1271 (2013.01); A61K 35/12 (2013.01); A61K 35/16 (2013.01); A61P 9/10 (2018.01); A61P 17/02 (2018.01); C12N 5/0634 (2013.01); G01N 33/5005 (2013.01); C12N 2502/00 (2013.01);
Abstract

The present invention relates to compositions of extracellular vesicles (EVs) which are characterized by a strong proangiogenic activity and are effective in the therapeutic treatment of ischemic diseases and ischemic injuries or in wound healing. The extracellular vesicles (EVs) suitable for use in the compositions of the invention are either derived from a blood component or are selected by means of a potency test for pro-angiogenesis. Also disclosed is a method of manufacturing a pharmaceutical preparation of extracellular vesicles (EVs) characterized by a strong proangiogenic activity.


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