The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2022

Filed:

Jul. 12, 2018
Applicants:

East China University of Science and Technology, Shanghai, CN;

Yunnan University, Kunming, CN;

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Inventors:

Honglin Li, Shanghai, CN;

Weilie Xiao, Kunming, CN;

Lili Zhu, Shanghai, CN;

Lina Quan, Shanghai, CN;

Qiao Li, Shanghai, CN;

Yanyan Diao, Shanghai, CN;

Zhenjiang Zhao, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/704 (2006.01); A61P 35/00 (2006.01); A61K 31/56 (2006.01);
U.S. Cl.
CPC ...
A61K 31/704 (2013.01); A61K 31/56 (2013.01); A61P 35/00 (2018.01);
Abstract

Provided are use of a saponin compound of formula (I) or (II), or a pharmaceutically acceptable salt, prodrug or solvate thereof, in the manufacture of a medicament targeting PD-1. The medicament targeting PD-1 is one which treats a disease by inhibiting PD-1 from binding to a ligand thereof. The disease may be a tumor, an infection caused by a bacterium, a virus or a fungus, or an inflammatory disease.


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