The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Oct. 19, 2017
Applicant:
Nektar Therapeutics, San Francisco, CA (US);
Inventors:
Wen Zhang, San Ramon, CA (US);
Jennifer Riggs-Sauthier, Huntsville, AL (US);
J. Milton Harris, Huntsville, AL (US);
Michael D. Bentley, Huntsville, AL (US);
Assignee:
Nektar Therapeutics, San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/573 (2006.01); C07J 41/00 (2006.01); A61K 47/60 (2017.01); A61K 47/59 (2017.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 47/59 (2017.08); A61K 47/60 (2017.08); C07J 41/0005 (2013.01);
Abstract
The invention provides corticosteroids that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the corticosteroid not attached to the water-soluble oligomer.