The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2022

Filed:

Feb. 24, 2010
Applicants:

Robert Davis, San Diego, CA (US);

Allen Fienberg, New York, NY (US);

Inventors:

Robert Davis, San Diego, CA (US);

Allen Fienberg, New York, NY (US);

Assignee:

INTRA-CELLULAR THERAPIES, INC., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 9/00 (2006.01); A61K 31/5575 (2006.01); A61P 27/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/535 (2013.01); A61K 9/0048 (2013.01); A61K 31/5575 (2013.01); A61P 27/06 (2018.01);
Abstract

Compounds that inhibit phosphodiesterase 1 (PDE1) are useful to treat glaucoma or elevated intraocular pressure. The PDE1 inhibitors may be administered as monotherapy or in combination with additional intraocular-pressure lowering agents. In addition, the invention provides ophthalmic compositions comprising PDE 1 inhibitors and optionally one or more additional intraocular pressure-lowering agents. Topical and systemic therapy may be used.


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