The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 11, 2022

Filed:

Jun. 21, 2018
Applicant:

Minerva Neurosciences, Inc., Burlington, MA (US);

Inventors:

Jay Saoud, Waltham, MA (US);

Remy Luthringer, Geneva, CH;

Sandra Werner, Ostwald, FR;

Nadine Noel, Gildwiller, FR;

Emmanuelle Georgi, Colmar, FR;

Assignee:

Minerva Neurosciences, Inc., Burlington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 31/454 (2006.01); A61K 9/28 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
A61K 9/205 (2013.01); A61K 9/2009 (2013.01); A61K 9/2018 (2013.01); A61K 9/2054 (2013.01); A61K 9/28 (2013.01); A61K 9/2846 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01);
Abstract

This disclosure relates to gastro-resistant, controlled release dosage forms comprising Compound (I): or a pharmaceutically acceptable salt and/or solvate thereof, the pharmacokinetic properties of these dosage forms, and the preparation of the same. The novel dosage forms disclosed herein are useful in reducing the risk of QT prolongation in a subject and in treating a disorder in a subject in need thereof, e.g., a subject diagnosed with schizophrenia, for example, in treating the negative symptoms in a subject diagnosed with schizophrenia having the CYP2D6 EM genotype.


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