The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Nov. 11, 2015
Applicant:

Cytiva Sweden Ab, Uppsala, SE;

Inventors:

Lena Nyholm, Uppsala, SE;

Johan Arthursson, Uppsala, SE;

Eva Olsson, Uppsala, SE;

Ulrika Ohman, Uppsala, SE;

Assignee:

Cytiva Sweden AB, Uppsala, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/86 (2006.01); G01N 30/26 (2006.01); G01N 30/50 (2006.01);
U.S. Cl.
CPC ...
G01N 30/8658 (2013.01); G01N 30/26 (2013.01); G01N 30/50 (2013.01); G01N 30/86 (2013.01);
Abstract

Method for determining the influence of least a first and a second experimental parameter on a liquid chromatography protocol for purifying one or more target molecules from a sample, comprising the steps: —performing chromatography purifications of the sample at a plurality of different experimental conditions where at least the first and the second experimental parameter each are varied over a predetermined range, each purification being registered as a chromatogram by monitoring an output parameter indicative of the purification result during the purification; and—displaying in a graphical user interface at least a subset of the registered chromatograms as chromatogram-miniatures in an evaluation diagram wherein the position of each displayed chromatogram-miniature is determined by the experimental parameters for the corresponding purification, thereby allowing a user to visually determine trends and the influence of the experimental parameters on the liquid chromatography protocol.


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