The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Jul. 08, 2014
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

George M. Church, Brookline, MA (US);

James Dicarlo, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/90 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/902 (2013.01); C12N 15/111 (2013.01); C12N 2310/20 (2017.05);
Abstract

Methods of multiplex genome engineering in cells using Cas9 is provided which includes a cycle of steps of introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to the target DNA and which guide the enzyme to the target DNA, wherein the one or more RNAs and the enzyme are members of a co-localization complex for the target DNA, and introducing into the cell a second foreign nucleic acid encoding one or more donor nucleic acid sequences, and wherein the cycle is repeated a desired number of times to multiplex DNA engineering in cells.


Find Patent Forward Citations

Church, George. (2022). Multiplex rna-guided genome engineering (U.S. Patent No. 11459585). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11459585

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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