The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Feb. 08, 2019
Applicants:

Consejo Nacional DE Investigaciones Científicas Y Técnicas (Conicet), Ciudad Autónoma de Buenos Aires, AR;

Universidad Nacional DE General San Martín, Pcia. de Buenos Aires, AR;

Inventors:

Mirta L. Coria, San Martín, AR;

Karina A. Pasquevich, Ciudad Autónoma de Buenos Aires, AR;

Juliana Cassataro, Ciudad Autónoma de Buenos Aires, AR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/39 (2006.01); A61P 37/04 (2006.01); C07K 14/255 (2006.01); C12N 15/79 (2006.01); A61K 39/112 (2006.01); A61K 9/00 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/79 (2013.01); A61K 39/0275 (2013.01); A61K 39/39 (2013.01); A61P 37/04 (2018.01); C07K 14/255 (2013.01); A61K 9/0029 (2013.01); A61K 9/0053 (2013.01); A61K 39/3955 (2013.01); A61K 2039/55516 (2013.01);
Abstract

The present invention relates to modified bacterial polypeptides having immunomodulatory and immunostimulatory activity. Most specifically, the present invention relates to modified bacterial polypeptides having an amino acid sequence selected from SEQ ID NO. 1, SEQ ID NO. 2, SEQ ID NO. 3, SEQ ID NO. 4 and SEQ ID NO. 5. The modified polypeptides are the adjuvant components of a pharmaceutical composition for eliciting an immune response against an specific antigen present in the pharmaceutical composition. In a preferred embodiment, the invention provides a pharmaceutical composition for a vaccine which comprises an adjuvant component which is any one of the modified polypeptides, one or more antigens, together with a pharmaceutically acceptable excipient.


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