The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Dec. 03, 2021
Applicant:

Macrogenics, Inc., Rockville, MD (US);

Inventors:

David Lee Farb, Chelmsford, MA (US);

Yan Zhou, Rockville, MD (US);

Krishnan Sampathkumar, North Potomac, MD (US);

Assignee:

MacroGenics, Inc., Rockville, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/32 (2006.01); A61K 47/02 (2006.01); A61P 35/00 (2006.01); A61K 47/26 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01); A61K 47/26 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention is directed in part to pharmaceutical compositions for storage and administration comprising a) a HER2/neu antibody ('margetuximab'), b) buffering agents, and c) stabilizers, wherein said margetuximab is stable. The invention in part provides, containers and kits comprising such pharmaceutical compositions. The invention is directed in part to the use of such pharmaceutical compositions, containers, and kits containing margetuximab in the treatment of HER2/neu-positive cancer (i.e., a cancer that expresses HER2), including breast cancer or gastric cancer or GEJ cancer.


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