The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Jan. 30, 2018
Applicant:

Ohio State Innovation Foundation, Columbus, OH (US);

Inventors:

Michael Caligiuri, Columbus, OH (US);

Jianhua Yu, Columbus, OH (US);

Hongsheng Dai, Columbus, OH (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); C07K 16/30 (2006.01); C12N 5/0786 (2010.01); A61K 38/08 (2019.01);
U.S. Cl.
CPC ...
C07K 16/087 (2013.01); A61K 38/08 (2013.01); C07K 16/088 (2013.01); C07K 16/30 (2013.01); C12N 5/0645 (2013.01); C07K 2317/52 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C12N 2533/50 (2013.01);
Abstract

In certain embodiments, described herein is a method of treating a subject infected with a pathogen encoding an Fc-binding protein comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Also described herein is a method for treating cancer in a subject undergoing oncolytic viral therapy comprising administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody. Further described herein is a method of activating natural killer (NK) cells in a subject infected with a pathogen, comprising administering to the subject a pharmaceutical composition comprising an Fc region of an immunoglobulin G antibody.


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