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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11459358 B1

PDFFull Text
Date of Patent:
Oct. 04, 2022

Filed:

Nov. 15, 2017

Substances for targeting various selected organs or tissues

Applicants:

Biomarin Technologies B.v., Leiden, NL;

Academisch Ziekenhuis Leiden, Leiden, NL;

Inventors:

Peter Christian De Visser, Leiden, NL;

Adriana Marie Aartsma-Rus, Hoofddorp, NL;

Silvana Maria Gerarda Jirka, Leiden, NL;

Peter Abraham Christiaan 'T Hoen, Nijmegen, NL;

Maria Begoña Aguilera Diez, Leiden, NL;

Assignee:

ACADEMISCH ZIEKENHUIS LEIDEN, Leiden, NL;

Attorney:

Husch Blackwell LLP

Primary Examiner:

Li N Komatsu

Int. Cl.
CPC ...
C07K 7/64 (2006.01); A61K 47/64 (2017.01); A61K 47/54 (2017.01); A61P 9/00 (2006.01); A61K 49/00 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); A61K 47/549 (2017.08); A61K 47/64 (2017.08); A61K 49/0043 (2013.01); A61K 49/0056 (2013.01); A61P 9/00 (2018.01); C12N 15/113 (2013.01); C07K 2319/09 (2013.01); C07K 2319/10 (2013.01); C12N 2310/11 (2013.01); C12N 2310/314 (2013.01); C12N 2310/315 (2013.01); C12N 2310/321 (2013.01); C12N 2310/346 (2013.01); C12N 2310/3513 (2013.01);
Abstract

The invention provides conjugates, comprising an organ or tissue targeting moiety linked to a biologically active moiety or linked to a diagnostic moiety. Such a biologically active or diagnostic moiety can be, for example, an oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical, or a detectable agent.

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De Visser, Peter. (2022). Substances for targeting various selected organs or tissues (U.S. Patent No. 11459358). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11459358

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