The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2022
Filed:
Nov. 23, 2018
Jubilant Episcribe Llc, Yardley, PA (US);
Saravanan Vadivelu, Bangalore, IN;
Sridharan Rajagopal, Bangalore, IN;
Raghunadha Reddy Burri, Bangalore, IN;
Shivani Garapaty, Bangalore, IN;
Dhanalakshmi Sivanandhan, Bangalore, IN;
Manish Kumar Thakur, Bangalore, IN;
Tamizharasan Natarajan, Bangalore, IN;
Indu N Swamy, Bangalore, IN;
Nagendra Nagaraju, Bangalore, IN;
Subramaniam Kanagaraj, Bangalore, IN;
Zainuddin Mohd, Bangalore, IN;
Sayantani Sarkar, Bangalore, IN;
Swapan Kumar Samanta, Bangalore, IN;
Hariprakash, Noida, IN;
JUBILANT EPISCRIBE LLC, Yardley, PA (US);
Abstract
The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therapeutic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.