The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Jan. 30, 2019
Applicant:

Takeda Pharmaceutical Company Limited, Osaka, JP;

Inventors:

Yuta Tanaka, Kanagawa, JP;

Tomohiro Ohashi, Kanagawa, JP;

Zenichi Ikeda, Kanagawa, JP;

Yuta Tanaka, Kanagawa, JP;

Florian Pünner, Kanagawa, JP;

Takeshi Yamamoto, Kanagawa, JP;

Keiko Kakegawa, Kanagawa, JP;

Fumiaki Kikuchi, Kanagawa, JP;

Nao Morishita, Kanagawa, JP;

Takahito Kasahara, Kanagawa, JP;

Masaki Seto, Kanagawa, JP;

Minoru Nakamura, Kanagawa, JP;

Kazuaki Takami, Kanagawa, JP;

Masataka Murakami, Kanagawa, JP;

Masaki Daini, Kanagawa, JP;

Satoshi Mikami, Kanagawa, JP;

Minoru Sasaki, Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 519/00 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61P 25/28 (2018.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a compound having a glucosylceramide lowering action (e.g., promoting glucosylceramide metabolism, inhibition of glucosylceramide synthesis, promoting glucosylceramide catabolism, etc.), which is expected to be useful as an agent for the prophylaxis or treatment of lysosome diseases (e.g., Gaucher's disease), neurodegenerative diseases (e.g., Parkinson's disease, Lewy body dementia, multiple-system atrophy) and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof.


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