The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Apr. 10, 2018
Applicant:

Ck Regeon Inc., Seoul, KR;

Inventors:

Kang-Yell Choi, Seoul, KR;

Gyoonhee Han, Seoul, KR;

Jeong-Ha Hwang, Seoul, KR;

Sehee Choi, Seoul, KR;

Changmok Oh, Seoul, KR;

Assignee:

CK REGEON INC., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61P 19/00 (2006.01); A61P 19/10 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 19/10 (2018.01);
Abstract

A composition for promoting longitudinal bone growth, according to the present invention, promotes the proliferation of the chondrocytes and the differentiation of the osteoblasts and has effects of simultaneously increasing longitudinal bone length and thickness (bone density), and thus has an advantage of being widely prescribable to various age groups, thereby being usable as a pharmaceutical composition for promoting the growth of longitudinal bone length and thickness. An indirubin derivative according to the present invention has prevention or treatment effects through oral administration. In addition, unlike conventional therapeutic agents, the pharmaceutical composition for preventing or treating bone diseases of the present invention is a stable compound, which is known to be substantially noncytotoxic to the human body, and is a material of which adverse effects have not been identified and has excellent treatment effects for bone diseases and osteogenesis imperfecta.


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