The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Nov. 13, 2020
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Christopher J. Bettinger, Palo Alto, CA (US);

Joost P. Bruggeman, Schorl, NL;

Lino Da Silva Ferreira, Cambridge, MA (US);

Jeffrey M. Karp, Chestnut Hill, MA (US);

Robert S. Langer, Newton, MA (US);

Christiaan Nijst, Amsterdam, NL;

Andreas Zumbuehl, Nyon, CH;

Jason Burdick, Philadelphia, PA (US);

Sonia J. Kim, West Nyack, NY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 63/685 (2006.01); C08J 3/24 (2006.01); C08K 5/00 (2006.01); A61L 31/06 (2006.01); A61L 27/18 (2006.01); A61L 27/38 (2006.01); A61L 27/58 (2006.01); C12N 11/096 (2020.01); C12N 11/087 (2020.01); A61K 35/12 (2015.01); A61K 35/48 (2015.01); A61K 45/06 (2006.01); A61L 31/14 (2006.01);
U.S. Cl.
CPC ...
A61L 31/06 (2013.01); A61K 35/12 (2013.01); A61K 35/48 (2013.01); A61K 45/06 (2013.01); A61L 27/18 (2013.01); A61L 27/38 (2013.01); A61L 27/58 (2013.01); A61L 31/148 (2013.01); C08G 63/6854 (2013.01); C08J 3/24 (2013.01); C08J 3/246 (2013.01); C08K 5/0025 (2013.01); C12N 11/087 (2020.01); C12N 11/096 (2020.01); C08J 2367/00 (2013.01); C08J 2367/07 (2013.01);
Abstract

The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.


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