The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 04, 2022
Filed:
Sep. 22, 2020
Applicant:
Erytech Pharma, Lyons, FR;
Inventors:
Yann Godfrin, Lyons, FR;
Vanessa Bourgeaux, Lyons, FR;
Fabien Gay, Lyons, FR;
Thomas Cortese, Labege, FR;
Assignee:
ERYTECH PHARMA, Lyons, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/18 (2015.01); A61K 38/51 (2006.01); A61K 9/50 (2006.01); A61K 31/675 (2006.01); A61K 38/45 (2006.01); C12N 9/88 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/18 (2013.01); A61K 9/5068 (2013.01); A61K 31/675 (2013.01); A61K 38/45 (2013.01); A61K 38/51 (2013.01); C12N 9/88 (2013.01); C12Y 206/01005 (2013.01); C12Y 404/01011 (2013.01); A61K 2035/124 (2013.01);
Abstract
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it. The pharmaceutical composition comprises erythrocytes and a pharmaceutically acceptable vehicle, the erythrocytes encapsulating the PLP-dependent enzyme. The PLP-dependent enzyme may be methioninase, tyrosine phenol-lyase, tyrosine aminotransferase or cystathionine beta-synthase.