The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 04, 2022

Filed:

Sep. 04, 2014
Applicant:

Vanda Pharmaceuticals Inc., Washington, DC (US);

Inventors:

Mihael H. Polymeropoulos, Potomac, MD (US);

Louis William Licamele, Potomac, MD (US);

Christian Lavedan, Potomac, MD (US);

Assignee:

VANDA PHARMACEUTICALS INC., Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/704 (2006.01); A61K 31/40 (2006.01); A61K 31/405 (2006.01); A61K 31/22 (2006.01); A61K 31/44 (2006.01); A61K 31/505 (2006.01); A61K 31/47 (2006.01); A61K 31/136 (2006.01); A61K 31/365 (2006.01); A61K 31/366 (2006.01); A61K 31/351 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/704 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/136 (2013.01); A61K 31/22 (2013.01); A61K 31/351 (2013.01); A61K 31/365 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 31/405 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01);
Abstract

The invention relates generally to the treatment of CYR61- and VEGF-mediated conditions and, more particularly to the treatment of such conditions by administering to an individual a CYR61 downregulator. In one embodiment, the invention provides a method of treating a CYR61-mediated condition in an individual in need of such treatment, the method comprising: administering to the individual an effective amount of at least one CYR61 downregulator (CYR61DR), wherein the effective amount is an amount sufficient to decrease expression of the CYR61 gene in the individual.


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