The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2022
Filed:
Jul. 08, 2019
Immunitybio, Inc., Culver City, CA (US);
Rohit Duggal, San Diego, CA (US);
Ranjeet Sinha, San Diego, CA (US);
Wenzhao Li, San Diego, CA (US);
Jason Isaacson, San Diego, CA (US);
Karl Marquez, San Diego, CA (US);
Patrick Soon-Shiong, San Diego, CA (US);
ImmunityBio, Inc., Culver City, CA (US);
Abstract
Cord blood or peripheral blood NK cells are prepared from whole blood mononuclear cells without the need to isolate CD34+ hematopoietic stem cells or NK cells, and without the need for a feeder layer. Advantageously, the methods presented herein use an enrichment process that uses antiCD16 agonist antibodies, antiCD3 antibodies, and N-803. Moreover, contemplated processes are suitable for adaptation into a fully automated production process (GMP in a box).