The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2022

Filed:

May. 21, 2020
Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Evangelos Aktoudianakis, Redwood City, CA (US);

Jayaraman Chandrasekhar, Redmond, WA (US);

Julian A. Codelli, Seattle, WA (US);

John H. Conway, Seattle, WA (US);

Kristyna M. Elbel, San Francisco, CA (US);

Rao V. Kalla, Cupertino, CA (US);

Samuel E. Metobo, Newark, CA (US);

Scott A. Mitchell, Kenmore, WA (US);

Thao D. Perry, San Jose, CA (US);

Scott P. Simonovich, San Francisco, CA (US);

Christopher A. Ziebenhaus, San Francisco, CA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present disclosure relates generally to certain ene-oxindole compounds, pharmaceutical compositions comprising thereof. Also disclosed are methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.


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