The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2022
Filed:
Apr. 18, 2019
Cellcentric Ltd, Cambridge, GB;
Paul Baguley, Abingdon, GB;
Donald Alan Gilbert, Sudbury, GB;
Gareth Harbottle, Nottingham, GB;
Colin Lindley, Abingdon, GB;
John Paul Madeley, Abingdon, GB;
James Vaughan Morey, Sudbury, GB;
David Michel Adrien Taddei, Nottingham, GB;
Jonathan Trevorrow, Abingdon, GB;
David Wood, Sudbury, GB;
CELLCENTRIC LTD, Cambridge, GB;
Abstract
A process for producing a compound of the following formula (I) which process comprises: (a) treating a compound of the following formula (5) with a compound of the following formula (6) to generate an intermediate compound of the following formula (7); (b) treating a compound of formula (7) as defined above with a compound of the following formula (8); and (c) recovering a compound of formula (I) as defined above. The compound of formula (I) is a promising modulator of p300/CBP activity that has potential utility in treating cancers, including prostate cancer, haematological cancers, bladder cancer and lung cancer.