The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2022
Filed:
Aug. 17, 2020
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Alexander Russell Abela, San Diego, CA (US);
Timothy Alcacio, San Diego, CA (US);
Corey Anderson, San Diego, CA (US);
Paul Timothy Angell, Carlsbad, CA (US);
Minson Baek, San Diego, CA (US);
Jeremy J. Clemens, San Diego, CA (US);
Thomas Cleveland, San Marcos, CA (US);
Lori Ann Ferris, Wilmington, MA (US);
Peter Diederik Jan Grootenhuis, Del Mar, CA (US);
Raymond Stanley Gross, Poway, CA (US);
Anton V. Gulevich, San Diego, CA (US);
Sara Sabina Hadida Ruah, La Jolla, CA (US);
Clara Kuang-Ju Hsia, San Diego, CA (US);
Robert M. Hughes, San Diego, CA (US);
Pramod Virupax Joshi, San Diego, CA (US);
Ping Kang, San Diego, CA (US);
Ali Keshavarz-Shokri, San Diego, CA (US);
Haripada Khatuya, San Diego, CA (US);
Paul John Krenitsky, San Diego, CA (US);
Jason McCartney, Cardiff by the Sea, CA (US);
Mark Thomas Miller, San Diego, CA (US);
Prasuna Paraselli, San Diego, CA (US);
Fabrice Jean Denis Pierre, La Jolla, CA (US);
Yi Shi, Natick, MA (US);
Muna Shrestha, Belmont, MA (US);
David Andrew Siesel, San Diego, CA (US);
Kathy Stavropoulos, Quincy, MA (US);
Andreas P. Termin, Encinitas, CA (US);
Fredrick F. Van Goor, San Diego, CA (US);
Johnny Uy, San Diego, CA (US);
Timothy John Young, San Diego, CA (US);
Jinglan Zhou, San Diego, CA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
Compounds of Formula (I): pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.