The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2022

Filed:

Feb. 13, 2018
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Birgit Bollbuck, Munich, DE;

Christian Markert, Riehen, CH;

Wolfgang Miltz, Basel, CH;

Till Roehn, Zurich, CH;

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/415 (2006.01); A61K 31/422 (2006.01); A61K 31/4245 (2006.01); A61K 31/428 (2006.01); C07D 231/12 (2006.01); C07D 271/10 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 257/04 (2006.01); A61K 45/06 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
C07D 257/04 (2013.01); A61K 31/41 (2013.01); A61K 31/415 (2013.01); A61K 31/422 (2013.01); A61K 31/428 (2013.01); A61K 31/4245 (2013.01); A61K 31/4439 (2013.01); A61K 45/06 (2013.01); C07D 231/12 (2013.01); C07D 271/10 (2013.01); C07D 401/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.


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