The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2022

Filed:

Dec. 20, 2019
Applicant:

Northwestern Polytechnical University, Xi 'an, CN;

Inventors:

Lianbing Zhang, Xi 'an, CN;

Yingchun Yang, Xi 'an, CN;

Qing Tian, Xi 'an, CN;

Aipeng Li, Xi 'an, CN;

Yao Chen, Xi 'an, CN;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61K 9/1641 (2013.01); A61K 9/1694 (2013.01); A61P 31/04 (2018.01); A61P 35/00 (2018.01);
Abstract

The present invention discloses a method for synthesizing a new ferrihydrite nano-photosensitizer, comprising steps of: weighing 303 mg of Fe(NO)⋅9HO solid dissolved fully in 30 ml of distilled water to prepare a 0.75 mM of Fe(NO)solution in water; adding PEG solid to the solution in water by stirring to fully dissolve at a molar ratio of PEG to Feof 1:1-1:50; stirring the obtained solution under heating at 75° C. in a water bath for 10-50 minutes, and then immediately cooling in an ice bath after removing; centrifuging and washing the cooled mixed solution at high speed under low temperature with the supernatant discarded, to obtain pellets as PEG-modified ferrihydrite nanoparticles (PEG-Fns). The PEG-Fns synthesized in the present invention can be controllably induced and reduced by blue light to release Fe, and then produce ⋅OH through Fenton reaction of Feand HOin the cell, which induces cell oxidative damage, thereby achieving controllable anticancer and antibacterial purposes.


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Zhang, Lianbing. (2022). Method for synthesizing a new ferrihydrite nano-photosensitizer and its antibacterial and anticancer use (U.S. Patent No. 11452777). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11452777

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