The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 27, 2022
Filed:
Jan. 03, 2020
Applicant:
Empirico Inc., San Diego, CA (US);
Inventors:
Omri Gottesman, San Diego, CA (US);
Shannon Bruse, San Diego, CA (US);
Brian Cajes, San Diego, CA (US);
David Lewis, Madison, WI (US);
David Rozema, Cross Plains, WI (US);
Assignee:
EMPIRICO INC., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/7125 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7125 (2013.01); C12N 15/1136 (2013.01); C12N 2310/11 (2013.01); C12N 2310/14 (2013.01); C12N 2310/315 (2013.01); C12N 2310/341 (2013.01); C12N 2310/343 (2013.01); C12N 2310/346 (2013.01); C12N 2320/11 (2013.01);
Abstract
Provided are compositions comprising an oligonucleotide that targets Thymic stromal lymphopoietin (TSLP). The oligonucleotide may include a small interfering RNA (siRNA) or an antisense oligonucleotide (ASO). Also provided herein are methods of treating an airway disorder by providing an oligonucleotide that targets TSLP to a subject in need thereof. In some embodiments, the oligonucleotide targeting is specific for a long isoform of TSLP (1fTSLP).