The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2022

Filed:

Apr. 22, 2022
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Dafydd Rhys Owen, Concord, MA (US);

Matthew Richard Reese, Mystic, CT (US);

Matthew Forrest Sammons, Quincy, MA (US);

Jamison Bryce Tuttle, Marblehead, MA (US);

Patrick Robert Verhoest, Newton, MA (US);

Qingyi Yang, Lexington, MA (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/403 (2006.01); A61P 31/14 (2006.01); A61K 31/427 (2006.01); A61K 31/401 (2006.01);
U.S. Cl.
CPC ...
A61K 31/403 (2013.01); A61K 31/401 (2013.01); A61K 31/427 (2013.01); A61P 31/14 (2018.01); C07D 403/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention relates to compounds of Formula I″ wherein R, R, R, R, p, q and q' are as defined herein, pharmaceutical compositions comprising the compounds, methods of treating coronavirus infection such as COVID-19 in a patient by administering therapeutically effective amounts of the compounds, and methods of inhibiting or preventing replication of coronaviruses such as SARS-CoV-2 with the compounds.


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