The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 27, 2022

Filed:

Sep. 24, 2021
Applicant:

Arun Ananth Aiyer, Fremont, CA (US);

Inventor:

Arun Ananth Aiyer, Fremont, CA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61B 5/145 (2006.01); A61B 5/1495 (2006.01); A61B 5/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/1455 (2013.01); A61B 5/1495 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/7246 (2013.01); A61B 2562/0238 (2013.01);
Abstract

A sensor device which is adapted for detecting target molecules in-vitro and in-vivo, comprises a MIR source emitting in 2 um to 10 um range for exciting the target species and a probe beam with orthogonal polarizations and split frequencies in the KHz. to MHz range. The probe beam measures the effects of specie concentration change and of its excitation. The evanescent fields of the orthogonally polarized beams in the probe beam undergo differential phase shifts when target species concentration changes in epidermis or when its refractive index changes due to photo-thermal excitation by the MIR beam. The phase shift is directly proportional to concentration change and refractive index change and are measured using a heterodyne interferometer operating at the same frequency as the split frequency. The measured phase shift can be related to specie concentration change in target volume.


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