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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11450409 B1

PDFFull Text
Date of Patent:
Sep. 20, 2022

Filed:

Aug. 12, 2016

Determination of nfkb pathway activity using unique combination of target genes

Applicant:

Innosign B.v., Eindhoven, NL;

Inventor:

Hendrik Jan Van Ooijen, Eindhoven, NL;

Assignee:

InnoSIGN B.V., Eindhoven, NL;

Attorney:

Bond, Schoeneck & King, PLLC

Primary Examiner:

Eric S Dejong

Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16B 25/20 (2019.01); G01N 33/574 (2006.01); A61K 31/336 (2006.01); A61K 31/416 (2006.01); A61K 38/05 (2006.01); A61K 31/4985 (2006.01); A61K 31/573 (2006.01); G16B 25/00 (2019.01); G16B 5/00 (2019.01); C12Q 1/6886 (2018.01); G16B 40/00 (2019.01); G16B 5/20 (2019.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
G16B 25/20 (2019.02); A61K 31/336 (2013.01); A61K 31/416 (2013.01); A61K 31/4985 (2013.01); A61K 31/573 (2013.01); A61K 38/05 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57484 (2013.01); G16B 5/00 (2019.02); G16B 5/20 (2019.02); G16B 25/00 (2019.02); G16B 40/00 (2019.02); C12Q 2600/158 (2013.01); G01N 2800/60 (2013.01);
Abstract

A bioinformatics process which provides an improved means to detect NFkB cellular signaling pathway in a subject, such as a human, based on the expression levels of at least six unique target genes of the NFkB cellular signaling pathway measured in a sample. The invention includes an apparatus comprising a digital processor configured to perform such a method, a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such a method, and a computer program comprising program code means for causing a digital processing device to perform such a method. Kits are also provided for measuring expression levels of unique sets of NFkB cellular signaling pathway target genes.

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