The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Apr. 07, 2017
Massachusetts Institute of Technology, Cambridge, MA (US);
Sangeeta N. Bhatia, Lexington, MA (US);
Darrell J. Irvine, Arlington, MA (US);
Karl Dane Wittrup, Chestnut Hill, MA (US);
Andrew David Warren, Cambridge, MA (US);
Jaideep S. Dudani, Boston, MA (US);
Naveen K. Mehta, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
In some aspects, the disclosure provides compositions and methods for detecting and monitoring the activity of pro teases in vivo using affinity assays. The disclosure relates, in part, to the discovery that biomarker nanoparticles targeted to the lymph nodes of a subject are useful for the diagnosis and monitoring of certain medical conditions (e.g., metastatic cancer, infection with certain pathogenic agents).