The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Aug. 10, 2018
Applicant:
Life Technologies Corporation, Carlsbad, CA (US);
Inventors:
Jonathan M. Rothberg, Guilford, CT (US);
Wolfgang Hinz, Killingworth, CT (US);
John F. Davidson, Guilford, CA (US);
Antoine M. van Oijen, Needham, MA (US);
John Leamon, Stonington, CT (US);
Martin Huber, Carlsbad, CA (US);
Mark James Milgrew, Branford, CT (US);
James Bustillo, Castro Valley, CA (US);
Assignee:
LIFE TECHNOLOGIES CORPORATION, Carlsbad, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/414 (2006.01); C12Q 1/6874 (2018.01); H01L 21/82 (2006.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
G01N 27/4145 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); G01N 27/4148 (2013.01); H01L 21/82 (2013.01);
Abstract
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.