The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Aug. 21, 2018
Applicant:
Seven Bridges Genomics Inc., Cambridge, MA (US);
Inventor:
Deniz Kural, Cambridge, MA (US);
Assignee:
Seven Bridges Genomics Inc., Charlestown, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 20/20 (2019.01); G16B 20/00 (2019.01); G16B 30/10 (2019.01); C12Q 1/6886 (2018.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 1/6883 (2013.01); G16B 20/00 (2019.02); G16B 20/20 (2019.02); G16B 30/10 (2019.02); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01);
Abstract
The invention includes methods and systems for identifying diseased-induced mutations by producing multi-dimensional reference sequence constructs that account for variations between individuals, different diseases, and different stages of those diseases. Once constructed, these reference sequence constructs can be used to align sequence reads corresponding to genetic samples from patients suspected of having a disease, or who have had the disease and are in suspected remission. The reference sequence constructs also provide insight to the genetic progression of the disease.