The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Aug. 29, 2016
Applicant:

California Institute of Technology, Pasadena, CA (US);

Inventors:

Arjang Hassibi, Sunnyvale, CA (US);

Babak Hassibi, San Marino, CA (US);

Haris Vikalo, Pasadena, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6851 (2018.01); C12Q 1/686 (2018.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6851 (2013.01); C12Q 1/686 (2013.01); G01N 21/6408 (2013.01); G01N 21/6428 (2013.01); G01N 2021/6432 (2013.01); G01N 2021/6439 (2013.01);
Abstract

This invention provides methods and systems for measuring the concentration of multiple nucleic acid sequences in a sample. The nucleic acid sequences in the sample are simultaneously amplified, for example, using polymerase chain reaction (PCR) in the presence of an array of nucleic acid probes. The amount of amplicon corresponding to the multiple nucleic acid sequences can be measured in real-time during or after each cycle using a real-time microarray. The measured amount of amplicon produced can be used to determine the original amount of the nucleic acid sequences in the sample.


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