The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Oct. 17, 2014
Applicant:
Seegene, Inc., Seoul, KR;
Inventors:
Jong Yoon Chun, Seoul, KR;
Young Jo Lee, Seoul, KR;
Assignee:
SEEGENE, INC., Seoul, KR;
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12N 9/00 (2006.01); C07H 21/04 (2006.01); C12Q 1/6832 (2018.01); C12Q 1/682 (2018.01); C12Q 1/6834 (2018.01); C12Q 1/6823 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/6837 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6832 (2013.01); C12Q 1/682 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6823 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6837 (2013.01);
Abstract
The present invention relates to the detection of a target nucleic acid sequence from a DNA or a mixture of nucleic acids by a PCE-hCTO (PTO Cleavage and Extension using hCTO) assay on a solid phase. According to the present invention, the extended duplex is formed in a liquid phase in a target-dependent manner and then its presence is detected on a solid phase. Since hCTO is not immobilized onto a solid phase, the extended duplex is more effectively formed in a liquid phase.