The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Dec. 01, 2016
Applicant:

Her Majesty the Queen IN Right of Canada, As Represented BY the Minister of National Defence, Ottawa, CA;

Inventors:

J. Christopher Hall, Whistler, CA;

Ashley J. Meyers, Cambridge, CA;

Krishnaraj Tiwari, Guelph, CA;

Jyoti Latawa, Mont-Royal, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 16/16 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8258 (2013.01); C07K 16/16 (2013.01); C12N 15/8216 (2013.01); A61K 2039/505 (2013.01); C07K 2317/13 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/76 (2013.01);
Abstract

A method of making an antibody in plants that binds to ricin B chain is described. The method comprises (a) introducing a nucleic acid molecule encoding a heavy chain variable region of the antibody and a nucleic acid molecule encoding a light chain variable region of the antibody into a plant or plant cell; and (b) growing the plant or plant cell to obtain a plant that expresses the antibody or antibody fragment. The disclosure also relates to anti-ricin B chain antibodies and antibody fragments as well as methods of using same in therapy and prophylaxis.


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