The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Dec. 13, 2019
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventor:
Bin Liu, San Francisco, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); C12N 15/10 (2006.01); G01N 33/68 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); A61K 45/06 (2013.01); A61K 47/6801 (2017.08); A61K 47/6851 (2017.08); A61K 47/6889 (2017.08); A61K 49/00 (2013.01); C07K 16/005 (2013.01); C07K 16/2866 (2013.01); C07K 16/3069 (2013.01); C12N 15/1037 (2013.01); G01N 33/574 (2013.01); G01N 33/6854 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01); C07K 2317/32 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01); C40B 40/10 (2013.01);
Abstract
Methods are provided for identifying and selecting antibodies that are internalized into cells via the macropinocytosis pathway. Additionally antibodies that are internalized via this pathway are provided as well as immunoconjugates comprising such antibodies.