The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Apr. 25, 2019
Applicant:

Niigata University, Niigata, JP;

Inventors:

Eisaku Kondo, Niigata, JP;

Ken Saito, Niigata, JP;

Assignee:

NIIGATA UNIVERSITY, Niigata, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); A61K 49/00 (2006.01); C07K 7/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 47/64 (2017.08); A61K 49/0056 (2013.01); A61P 35/00 (2018.01); C07K 7/06 (2013.01);
Abstract

This peptide is composed of an amino acid sequence represented by general formula (I), and has a high degree of accumulation in cancer cells or cancer tissue in a digestive system. In general formula (I), Xis a peptide residue composed of an amino acid sequence of (a) or (b) below: (a) an amino acid sequence represented by any of SEQ ID NOs: 1 to 3, (b) an amino acid sequence including a sequence in which one or two amino acids have been deleted, substituted or added in an amino acid sequence represented by any of SEQ ID NOs: 1 to 3; Yis a peptide linker composed of an amino acid residue of at least 1 but not more than 10 amino acids, wherein each amino acid residue is independently a glycine residue, a proline residue, a serine residue, a cysteine residue or a lysine residue; Xis either a peptide residue composed of an amino acid sequence of (a) or (b) above, or a retro-inverso peptide residue thereof; and n11 represents an integer of at least 1 but not more than 9.X—(Y—X)   General formula (I):


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