The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Aug. 17, 2018
Applicant:
Cancer Research Technology Limited, London, GB;
Inventors:
Angelo Pugliese, Glasgow, GB;
Stuart Francis, Glasgow, GB;
Duncan McArthur, Glasgow, GB;
Mairi Sime, Glasgow, GB;
Justin Bower, Glasgow, GB;
Simone Belshaw, Glasgow, GB;
Assignee:
Cancer Research Technology Limited, London, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 519/00 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61P 35/04 (2018.01); C07D 471/04 (2013.01);
Abstract
The present application relates to a compound of Formula I, or a salt, hydrate or solvate thereof, as defined herein. The present compounds are found to have pharmacological effects, particularly at MRCK. Further provided are pharmaceutical compositions comprising said compounds. The present invention also relates to the use of these compounds as therapeutic agents, in particular, for the treatment and/or prevention of proliferative diseases, such as cancer.