The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Jun. 28, 2019
Applicant:

Histogen, Inc., San Diego, CA (US);

Inventors:

Alfred P. Spada, Carlsbad, CA (US);

Robert J. Ternansky, San Diego, CA (US);

Assignee:

Histogen, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/048 (2006.01); C07D 241/04 (2006.01); C07D 241/08 (2006.01); C07D 241/38 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 403/12 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 409/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); C07D 241/04 (2013.01); C07D 241/08 (2013.01); C07D 241/38 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to (S)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating e.g. cardiovascular, kidney, liver, lung, skin, joints, CNS, inflammatory and autoimmune diseases.


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