The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Mar. 12, 2020
Applicant:
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA (US);
Inventors:
Nicholas David Peter Cosford, San Diego, CA (US);
Dhanya Raveendra-Panickar, San Diego, CA (US);
Douglas J. Sheffler, San Diego, CA (US);
John Howard Hutchinson, San Diego, CA (US);
Reto Andreas Gadient, San Diego, CA (US);
Assignee:
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 277/20 (2006.01); C07D 285/08 (2006.01); C07D 249/08 (2006.01); A61K 31/426 (2006.01); A61K 31/433 (2006.01); A61K 31/4196 (2006.01); A61P 25/00 (2006.01); C07D 243/14 (2006.01); A61K 31/427 (2006.01); C07D 217/06 (2006.01); C07D 417/04 (2006.01); C07D 403/12 (2006.01); C07D 233/54 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 405/04 (2006.01); C07D 239/26 (2006.01); C07D 409/04 (2006.01); C07D 243/12 (2006.01); C07D 271/06 (2006.01); C07D 275/02 (2006.01); C07D 277/30 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); C07D 231/12 (2006.01); C07D 233/64 (2006.01); C07D 261/08 (2006.01); C07D 263/32 (2006.01); C07D 277/26 (2006.01); C07D 307/38 (2006.01); C07D 333/24 (2006.01); C07D 401/14 (2006.01); C07D 405/10 (2006.01); C07D 409/02 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 243/14 (2013.01); A61K 31/4196 (2013.01); A61K 31/426 (2013.01); A61K 31/427 (2013.01); A61K 31/433 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61P 25/00 (2018.01); C07D 217/06 (2013.01); C07D 231/12 (2013.01); C07D 233/54 (2013.01); C07D 233/64 (2013.01); C07D 239/26 (2013.01); C07D 243/12 (2013.01); C07D 249/08 (2013.01); C07D 261/08 (2013.01); C07D 263/32 (2013.01); C07D 271/06 (2013.01); C07D 275/02 (2013.01); C07D 277/20 (2013.01); C07D 277/26 (2013.01); C07D 277/30 (2013.01); C07D 285/08 (2013.01); C07D 307/38 (2013.01); C07D 333/24 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 405/10 (2013.01); C07D 409/02 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01);
Abstract
Provided herein are small molecule active metabotropic glutamate subtype-2 and -3 receptor negative allosteric modulators (NAMs), compositions comprising the compounds, and methods of using the compounds and compositions.